It  is a highly conserved, naturally occurring, water-soluble regenerative peptide that is found in all tissues and in all cell types, except red blood cellshttps://topgradesteroidsonline.com/index.php/product/buy -Thymosin-500 -online -thymosin-beta-4/

 Also,this hormone is  found in the blood and in other body fluids, including tears, saliva, cerebrospinal fluid, and wound fluids buy Thymosin-500 online

Both platelets and leukocytes release Tβ4 into the wound fluid such that the final concentration is 13 μg/mL

Although Tβ4 contains only 43 amino acids, it appears to have a wide range of regenerative activities and specific sites on the molecule have been shown to mediate these effects.

The Tβ4 has both the  chemically synthesized and recombinant forms which have shown efficacy for dermal healing in preclinical models and in human patients .

In addition, dimeric form has been found to accelerate the rate of dermal healing in an animal model more rapidly than that of the parent molecule buy Thymosin-500 online

Also,the Tβ4 has also shown repair and regenerative activity in a number of other injury models, such as traumatic brain injury, spinal cord injury, stroke, a model of multiple sclerosis, ischemic limbs, and cardiac damage due to ischemia.

DESCRIPTION

TB-500 is present in both capsule and injection forms.

Thymosin beta 4 (Tβ4), is  a major actin-sequestering protein that consists of 43 amino acids, is the most abundant member of the highly conserved β–thymosin family and controls cell morphogenesis and motility by regulating the dynamics of the actin cytoskeleton.

Furthermore,Tβ4 promotes healing throughout the body. It also has anti-inflammatory properties. Found naturally in higher concentrations at injury sites, the water-soluble protein can repair tissue damage and regulate cell migration to a site buy Thymosin-500 online

In addition,Thymosin beta-4 is a protein that in humans is encoded by the TMSB4X gene.

This protein consists (in humans) of 43 amino acids (sequence: SDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES) and has a molecular weight of 4921 g/mol

Furthermore, Thymosin-β₄ is a major cellular constituent in many tissues. Its intracellular concentration may reach as high as 0.5 mM. Following Thymosin α1, β₄ was the second of the biologically active peptides from Thymosin Fraction 5 to be completely sequenced and synthesized buy Thymosin-500 online.

IMPORTANCE

Firstly,Thymosin(TB-500) contains T cells which  are lymphocyte immune cells that protect the body from pathogens and cancer cells. T cells originate from bone marrow and mature in the thymus.

Secondly,They are important for cell mediated immunity and the activation of immune cells to fight infection.

Helper T cells are arguably the most important cells in adaptive immunity, as they are required for almost all adaptive immune responses. They not only help activate B cells to secrete antibodies and macrophages to destroy ingested microbes, but they also help activate cytotoxic T cells to kill infected target cells buy Thymosin-500 online.

Generally, THYMOSIN(TB-500)

1. -Builds new blood vessels
2. -Regenerates muscle tissue fibres
3. -increases new cell growth
4. -key component in lymphocytes hence vital  in the defense mechanism
5. -Increases strength through muscle growth
6. -Improves endurance
7. -Speeds up the healing process for wounds buy Thymosin-500 online
8. -Reduces acute/chronic pain and/or inflammation
9. -Increases flexibility
10. -Increases hair growth
11. differentiation of endothelial cells (blood and lymphatic vessels)
12. growth of new blood cells
13. keratinocyte migration
14. collagen deposition
15. decreases inflammation in various tissue types
16. decreased inflamation in joints
17. increase muscle growth
18. increases in endurance and strength
19. relaxed muscle spasm and improved muscle tone
20. repair damaged heart tissue following a heart attack
21. healing of ulcers and lesions (including stomach and intestinal ulcers)
22. increased exchange of substance between cells
23. overall tissue repair
24. faster healing of wounds
25. repair of tendons and ligaments
26. improved flexibility of joints
27. prevents the formations of adhesions and fibrous bands in muscles, tendons and ligaments
28. protects and restores neurons after brain injury buy Thymosin-500 online

For Biological activities of thymosin, it is important in ;

Tissue regeneration.

Actin binding

Anti-inflammatory role for sulfoxide

Maturation of cells:

Thymosin β₄ induces the activity of the enzyme terminal deoxynucleotidyl transferase in populations of thymocytes (thymus-derived lymphocytes). This suggests that the peptide may contribute to the maturation of these cells buy Thymosin-500 online

Dosage

Firstly,Dosage depends on the purpose and severity of the injury / damage you are treating.

Also,People generally use between 4 to 8 mg of TB500 per week during the initial (loading) period of 4 to 6 weeks. Afterwards some opt to maintain the effects with a low 2 to 6 mg dose once every 2 weeks. The effects of TB-500 wear off within 2 – 3 weeks of injection.

1. TB-500 loading phase:

• • • duration: between 4 – 6 weeks
    • dosage: between 4 – 8 mg of TB-500 per week
    • frequency of injection:2 mg per injection, between 2 – 4 times per week (depending on the total weekly dosage)

2. TB-500 maintainance phase:

• • duration: as long as needed
  • dosage: between 2 – 6 mg of TB-500 per 2 weeks
  • frequency of injection:2 mg per injection, between 2 – 3 times per 2 weeks (depending on the total bi-weekly dosage)

TB-500 Storage temperatures

Before reconstitution (lyophilized / freeze dried powder):

• refrigerated between 2 – 8 degrees celsius (36 – 46 Fahrenheit) it’s good for 24 months
• at room temperature (up to 37 degrees Celsius or 98.6 Fahrenheit) it’s good for over 90 days
• up to 45 degrees Celsius or 113 Fahrenheit it’s good for about a week buy Thymosin-500 online

After reconstitution (liquid):

• liquid TB-500 should be refrigerated between 2 – 8 degrees celsius (36 – 46 Fahrenheit) at all times. Do not freeze it.
• reconstituted TB-500 should be used within 8 days https://topgradesteroidsonline.com/index.php/product/buy -Thymosin-500 -online -thymosin-beta-4/